Tuesday, June 20, 2017

Vaccine that lowers cholesterol offers hope of immunizing against cardiovascular disease

Posted: 19 Jun 2017 03:00 AM PDT
A vaccine to immunise people against high levels of cholesterol and the narrowing of the arteries caused by build-up of fatty material (atherosclerosis) may be possible following successful results in mice. Now, a phase I trial in patients has started to see if the findings translate to humans. The study, which is published today in the European Heart Journal [1], is the first to show that it is possible to immunise genetically modified mice with a molecule that causes the body to produce antibodies