New study strengthens evidence of the connection between statin use and cataracts

Posted: 02 Dec 2014 01:00 AM PST

Few classes of drugs have had such a transformative effect on the prevention of cardiovascular disease (CVD) as have statins, prescribed to reduce total cholesterol and low-density lipoprotein cholesterol. However, some clinicians have ongoing concerns regarding the potential for lens opacities (cataracts) as a result of statin use. In an article in the Canadian Journal of Cardiology, researchers report increased risk for cataracts in patients treated with statins.

Vegetable oil ingredient key to destroying gastric disease bacteria

Posted: 25 Nov 2014 01:00 PM PST

The bacterium Helicobacter pylori is strongly associated with gastric ulcers and cancer. To combat the infection, researchers at University of California, San Diego School of Medicine and Jacobs School of Engineering developed LipoLLA, a therapeutic nanoparticle that contains linolenic acid, a component in vegetable oils.

Only half of patients take their medications as prescribed

Posted: 23 Nov 2014 01:00 PM PST

Here is what we know: If people take medications prescribed to them, they usually get better. But only about half of all patients prescribed medication take it according to directions. Here is what we don't know: We don't know how to get patients to take their medications, despite many studies looking at the issue.

Chemical in coffee may help prevent obesity-related disease

Posted: 14 Nov 2014 04:00 AM PST

Researchers at the University of Georgia have discovered that a chemical compound commonly found in coffee may help prevent some of the damaging effects of obesity. In a paper published recently in Pharmaceutical Research, scientists found that chlorogenic acid, or CGA, significantly reduced insulin resistance and accumulation of fat in the livers of mice who were fed a high-fat diet.

Analgesics and anti-inflammatory drugs may have an impact on depression

Posted: 21 Oct 2014 02:00 PM PDT

Ordinary over the counter painkillers and anti-inflammatory drugs purchased from pharmacies may also be effective in the treatment of people suffering of depression. This is shown by the largest ever meta-analysis that has just been published by a research group from Aarhus University in the journal JAMA Psychiatry.

Oxidized LDL might actually be 'good guy'

Posted: 05 Sep 2014 02:00 AM PDT

A team of investigators at the University of Kentucky has made a thought-provoking discovery about a type of cholesterol previously believed to be a "bad guy" in the development of heart disease and other conditions. Jason Meyer, a University of Kentucky MD-PhD candidate, worked with Deneys van der Westhuyzen, Ph.D., a Professor in the Departments of Internal Medicine and Molecular and Cellular Biochemistry, to study the role oxidized LDL plays in the development of plaque inside artery walls.

Wine only protects against CVD in people who exercise

Posted: 01 Sep 2014 08:00 AM PDT

Wine only protects against cardiovascular disease (CVD) in people who exercise, according to results from the In Vino Veritas (IVV) study presented at ESC Congress by Professor Milos Taborsky from the Czech Republic. Professor Taborsky said: "This is the first randomised trial comparing the effects of red and white wine on markers of atherosclerosis (1) in people at mild to moderate risk of CVD.

Experts denounce clinical trials of unscientific, 'alternative' medicines

Posted: 21 Aug 2014 12:00 AM PDT

Experts writing in the Cell Press journal Trends in Molecular Medicine on August 20th call for an end to clinical trials of "highly implausible treatments" such as homeopathy and reiki. Over the last two decades, such complementary and alternative medicine (CAM) treatments have been embraced in medical academia despite budget constraints and the fact that they rest on dubious science, they say.

Aspirin may slow recurrence in breast cancer patients

Posted: 15 Aug 2014 05:00 AM PDT

New findings published in the journal Cancer Research reveal that some postmenopausal overweight breast cancer patients who use common anti-inflammatory drugs like aspirin or ibuprofen have significantly lower breast cancer recurrence rates. Researchers from the Cancer Therapy & Research Center at The University of Texas Health Science Center at San Antonio and the University of Texas at Austin began by examining blood serum from CTRC breast cancer patients, said CTRC oncologist Andrew Brenner, M.D., Ph.D.

Study shows type 2 diabetics can live longer than people without the disease

Posted: 08 Aug 2014 02:00 AM PDT

Patients treated with a drug widely prescribed for type 2 diabetes can live longer than people without the condition, a large-scale study involving over 180,000 people has shown. The findings indicate that a drug known as metformin, used to control glucose levels in the body and already known to exhibit anticancer properties, could offer prognostic and prophylactic benefits to people without diabetes.

Aspirin: Scientists believe cancer prevention benefits outweigh harms

Posted: 06 Aug 2014 04:00 AM PDT

New research from Queen Mary University of London (QMUL) reveals taking aspirin can significantly reduce the risk of developing - and dying from - the major cancers of the digestive tract, i.e. bowel, stomach and oesophageal cancer. For the first time, scientists have reviewed all the available evidence from many studies and clinical trials assessing both the benefits and harms of preventive use of aspirin.

Pepper and halt: Spicy chemical may inhibit gut tumors

Posted: 03 Aug 2014 02:00 PM PDT

Researchers at the University of California, San Diego School of Medicine report that dietary capsaicin - the active ingredient in chili peppers - produces chronic activation of a receptor on cells lining the intestines of mice, triggering a reaction that ultimately reduces the risk of colorectal tumors. The findings are published in the August 1, 2014 issue of The Journal of Clinical Investigation.

Rosemary and oregano contain diabetes-fighting compounds

Posted: 24 Jul 2014 12:00 AM PDT

The popular culinary herbs oregano and rosemary are packed with healthful compounds, and now lab tests show they could work in much the same way as prescription anti-diabetic medication, scientists report. In their new study published in ACS' Journal of Agricultural and Food Chemistry, they found that how the herbs are grown makes a difference, and they also identified which compounds contribute the most to this promising trait.

Niacin too dangerous for routine cholesterol therapy

Posted: 21 Jul 2014 02:00 AM PDT

After 50 years of being a mainstay cholesterol therapy, niacin should no longer be prescribed for most patients due to potential increased risk of death, dangerous side effects and no benefit in reducing heart attacks and strokes, writes Northwestern Medicine® preventive cardiologist Donald Lloyd-Jones, M.D., in a New England Journal of Medicine editorial.

Taking B vitamins won't prevent Alzheimer's disease

Posted: 16 Jul 2014 02:00 AM PDT

Taking B vitamins doesn't slow mental decline as we age, nor is it likely to prevent Alzheimer's disease, conclude Oxford University researchers who have assembled all the best clinical trial data involving 22,000 people to offer a final answer on this debate. High levels in the blood of a compound called homocysteine have been found in people with Alzheimer's disease, and people with higher levels of homocysteine have been shown to be at increased risk of Alzheimer's disease.

Is the next 'new' cancer drug already in your medicine cabinet?

Posted: 30 Jun 2014 02:00 PM PDT

It turns out that the same types of drugs that help reduce watery eyes and runny noses during allergy season might also help ward off tumors too. A new research report appearing in the July 2014 issue of The Journal of Leukocyte Biology suggests that antihistamines may have significant anti-cancer properties as they interfere with the function of a type of cell that is known to reduce the body's ability to fight tumors (called "myeloid derived suppressor cells").

Anti-diabetic drug slows aging and lengthens lifespan

Posted: 03 Jun 2014 02:00 PM PDT

A study by Belgian doctoral researcher Wouter De Haes (KU Leuven) and colleagues provides new evidence that metformin, the world's most widely used anti-diabetic drug, slows ageing and increases lifespan. In experiments reported in the journal Proceedings of the National Academy of Sciences, the researchers tease out the mechanism behind metformin's age-slowing effects: the drug causes an increase in the number of toxic oxygen molecules released in the cell and this, surprisingly, increases cell robustness and longevity in the long term.

Aspirin can reduce colorectal cancer risks for those with specific gene

Posted: 23 Apr 2014 02:00 PM PDT

The humble aspirin may have just added another beneficial effect beyond its ability to ameliorate headaches and reduce the risk of heart attacks: lowering colon cancer risk among people with high levels of a specific type of gene. The extraordinary finding comes from a multi-institutional team that analyzed data and other material from two long-term studies involving nearly 128,000 participants.

Psychological side-effects of anti-depressants worse than thought

Posted: 25 Feb 2014 01:00 PM PST

A University of Liverpool researcher has shown that thoughts of suicide, sexual difficulties and emotional numbness as a result of anti-depressants may be more widespread than previously thought. In a survey of 1,829 people who had been prescribed anti-depressants, the researchers found large numbers of people - over half in some cases - reporting on psychological problems due to their medication, which has led to growing concerns about the scale of the problem of over-prescription of these drugs.

Grape seed promise in fight against bowel cancer

Posted: 16 Feb 2014 01:00 PM PST

University of Adelaide research has shown for the first time that grape seed can aid the effectiveness of chemotherapy in killing colon cancer cells as well as reducing the chemotherapy's side effects. Published in the journal PLOS ONE, the researchers say that combining grape seed extracts with chemotherapy has potential as a new approach for bowel cancer treatment - to both reduce intestinal damage commonly caused by cancer chemotherapy and to enhance its effect.